Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140485 | 0.93 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL3148925 | 0.90 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL3140560 | 0.88 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL3141584 | 0.87 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL3148553 | 0.87 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL3138475 | 0.86 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL3149778 | 0.86 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL3148770 | 0.86 | MAPK14 (0.50) | MAPK14 | |
| SCHEMBL3148818 | 0.86 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL3148880 | 0.86 | MAPK14 (0.49) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699800-B1 | BICYCLIC HETEROCYCLIC P-38 KINASE INHIBITORS | NOVARTIS AG (CH) | 2010-02-10 | — | — | EP | claimed |