SCHEMBL31488024

SCHEMBL31488024

N=C(N)NS(=O)(=O)Nc1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CES1 P23141 1/20 0.47
KIF11 P52732 1/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
PRMT1 Q99873 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487701 0.82 CA1 (0.53) CA1CA2CA12CA9F2
SCHEMBL27640456 0.81 TMPRSS6 (0.51) CA1CA2POLBMEN1KMT2A
SCHEMBL3204466 0.78 POLB (0.52) CA1CA2CES1KIF11NPC1
SCHEMBL10633357 0.74 FLT1 (0.58) CA1CA2CES1MEN1KMT2A
SCHEMBL1645913 0.70 CA1 (1.00) CA1CA2CES1KIF11PRMT1
SCHEMBL3088460 0.70 CA1 (0.61) CA1CA2CES1KIF11NPC1
SCHEMBL1186622 0.70 NPC1 (0.61) CA1CA2NPC1MEN1KMT2A
SCHEMBL11707345 0.69 CA1 (0.67) CA1CA2CES1KIF11NPC1
SCHEMBL27183135 0.69 CA1 (0.59) CA1CA2CES1KIF11NPC1
SCHEMBL193624 0.68 KDM4E (0.35) CA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841747-A Guanidine compound containing fluorosulfonyl group, and preparation method and application thereof 上海交通大学 2025-04-18 CN disclosed