Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489075 | 0.91 | NAMPT (0.79) | NAMPT | |
| SCHEMBL31488928 | 0.88 | NAMPT (0.72) | NAMPT | |
| SCHEMBL31489130 | 0.88 | NAMPT (0.72) | NAMPTNPC1ALDH1A1MAPTHPGD | |
| SCHEMBL31489158 | 0.87 | NAMPT (0.71) | NAMPT | |
| SCHEMBL31488942 | 0.87 | NAMPT (0.74) | NAMPTNPC1ALDH1A1MAPTHPGD | |
| SCHEMBL3707364 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL31488913 | 0.85 | NAMPT (0.79) | NAMPTNPC1ALDH1A1MAPTHPGD | |
| SCHEMBL31488997 | 0.84 | NAMPT (0.75) | NAMPT | |
| SCHEMBL3701683 | 0.82 | NAMPT (0.92) | NAMPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL22325022 | 0.82 | NAMPT (0.71) | NAMPTNPC1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |