SCHEMBL31488892

SCHEMBL31488892

COCCS(=O)(=O)N1CCC(c2ccc(NC(=O)N3Cc4cc(F)cnc4C3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488811 0.86 NAMPT (0.56) NAMPT
SCHEMBL31488917 0.84 NAMPT (0.75) NAMPT
SCHEMBL31489066 0.83 NAMPT (0.67) NAMPT
SCHEMBL31488805 0.83 NAMPT (0.67) NAMPT
SCHEMBL31489153 0.83 NAMPT (0.48) NAMPT
SCHEMBL31489036 0.82 NAMPT (0.58) NAMPT
SCHEMBL31488788 0.81 NAMPT (0.53) NAMPT
SCHEMBL31488832 0.78 NAMPT (0.65) NAMPT
SCHEMBL31488809 0.78 NAMPT (0.67) NAMPT
Hydrochloric Acid SCHEMBL31489048 0.78 NAMPT (0.64) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed