SCHEMBL31489043

SCHEMBL31489043

NS(=O)(=O)N1CCC(c2ccc(NC(=O)N3Cc4ccc(F)cc4C3)cc2)CC1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488802 0.89 NAMPT (0.77) NAMPT
SCHEMBL31489079 0.88 NAMPT (0.78) NAMPT
SCHEMBL31488940 0.87 NAMPT (0.77) NAMPT
SCHEMBL31488857 0.85 NAMPT (0.74) NAMPT
SCHEMBL31488993 0.85 NAMPT (0.74) NAMPT
SCHEMBL31488949 0.85 NAMPT (0.74) NAMPT
SCHEMBL31488787 0.85 NAMPT (0.73) NAMPT
SCHEMBL31488800 0.85 NAMPT (0.73) NAMPT
SCHEMBL31488905 0.85 NAMPT (0.73) NAMPT
SCHEMBL31488831 0.85 NAMPT (0.73) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed