SCHEMBL31489077

SCHEMBL31489077

CC(C)(O)CNC(=O)C(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccc(F)cc4C3)cc2)CC1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488820 0.92 NAMPT (0.58) NAMPT
SCHEMBL31488908 0.91 NAMPT (0.53) NAMPT
SCHEMBL31489023 0.86 NAMPT (0.55) NAMPT
SCHEMBL31489032 0.86 NAMPT (0.57) NAMPT
SCHEMBL31489068 0.85 NAMPT (0.58) NAMPT
SCHEMBL31488925 0.85 NAMPT (0.66) NAMPT
SCHEMBL31488913 0.83 NAMPT (0.79) NAMPT
SCHEMBL31489167 0.83 NAMPT (0.61) NAMPT
SCHEMBL31489080 0.83 NAMPT (0.64) NAMPT
SCHEMBL31488853 0.82 NAMPT (0.77) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed