SCHEMBL31489119

SCHEMBL31489119

O=C(Nc1ccc(C2=CCN(C(=O)C3CCS(=O)(=O)CC3)CC2)cc1)N1Cc2ccc(F)cc2C1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3702048 0.89 NAMPT (1.00) NAMPT
SCHEMBL31488790 0.86 NAMPT (0.59) NAMPT
SCHEMBL3701666 0.85 NAMPT (1.00) NAMPT
SCHEMBL3703926 0.85 NAMPT (1.00) NAMPT
SCHEMBL31489089 0.84 NAMPT (0.63) NAMPT
SCHEMBL31488925 0.82 NAMPT (0.66) NAMPT
SCHEMBL3706310 0.82 NAMPT (1.00) NAMPT
SCHEMBL3702049 0.82 NAMPT (0.85) NAMPT
SCHEMBL3703455 0.79 NAMPT (1.00) NAMPT
SCHEMBL31489167 0.79 NAMPT (0.61) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed