SCHEMBL31489165

SCHEMBL31489165

CC(C)(O)CCS(=O)(=O)C12CCC(c3ccc(NC(=O)N4Cc5cc(F)cnc5C4)cc3)(CC1)CC2

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 13/20 0.42
MOGAT2 Q3SYC2 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488813 0.88 NAMPT (0.55) NAMPTMOGAT2
SCHEMBL31489141 0.85 NAMPT (0.36) NAMPTMOGAT2
SCHEMBL31489170 0.83 NAMPT (0.51) NAMPT
SCHEMBL31489110 0.83 NAMPT (0.44) NAMPT
SCHEMBL31489033 0.80 NAMPT (0.51) NAMPT
SCHEMBL31489176 0.80 NAMPT (0.45) NAMPT
SCHEMBL31488982 0.79 NAMPT (0.45) NAMPT
SCHEMBL31488850 0.79 NAMPT (0.40) NAMPTMOGAT2
SCHEMBL31489259 0.78 NAMPT (0.42) NAMPT
SCHEMBL31488911 0.77 NAMPT (0.52) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed