SCHEMBL31489481

SCHEMBL31489481

COc1c(-c2cncc(-c3cn([C@H](c4ccc(F)cc4)C(C)(F)F)nc3C)n2)ccn2nc(N)nc12

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.32
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489709 0.93 JAK2 (0.34) JAK2
SCHEMBL31489830 0.90
SCHEMBL31489355 0.90
SCHEMBL31489422 0.90
SCHEMBL31489434 0.88
SCHEMBL31489753 0.82 JAK2 (0.32) JAK2
SCHEMBL31489187 0.82 PIK3CG (0.42)
SCHEMBL31489688 0.82 PIK3CG (0.42)
SCHEMBL31489943 0.80 PIK3CG (0.36)
SCHEMBL31489251 0.80 PIK3CG (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed