SCHEMBL31489492

SCHEMBL31489492

CC(C)(O)C12CCC(c3ccc(NC(=O)N4Cc5ccc(F)cc5C4)cc3)(CC1)CC2

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489094 0.87 NAMPT (0.60) NAMPT
SCHEMBL31488915 0.86 NAMPT (0.57) NAMPT
SCHEMBL31489172 0.85 NAMPT (0.56) NAMPT
SCHEMBL31488919 0.85 NAMPT (0.57) NAMPT
SCHEMBL31488793 0.84 NAMPT (0.53) NAMPT
SCHEMBL31488810 0.84 NAMPT (0.68) NAMPT
Bromide SCHEMBL31489041 0.84 NAMPT (0.56) NAMPT
SCHEMBL31489031 0.84 NAMPT (0.56) NAMPT
SCHEMBL31488846 0.83 NAMPT (0.54) NAMPT
SCHEMBL31489067 0.82 NAMPT (0.55) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed