SCHEMBL31489499

SCHEMBL31489499

CC(C)(C)OC(=O)NC(C)(C)C(=O)N1CC=C(c2ccc(NC(=O)N3Cc4cc(F)cnc4C3)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488984 0.90 NAMPT (0.70) NAMPT
SCHEMBL31489129 0.88 NAMPT (0.62) NAMPT
SCHEMBL31488867 0.87 NAMPT (0.68) NAMPT
SCHEMBL31488903 0.85 NAMPT (0.58) NAMPT
SCHEMBL31489115 0.85 NAMPT (0.51) NAMPT
SCHEMBL31488938 0.85 NAMPT (0.50) NAMPT
Trifluoroacetic Acid SCHEMBL31489105 0.83 NAMPT (0.53) NAMPT
SCHEMBL31488962 0.80 NAMPT (0.70) NAMPT
SCHEMBL31488960 0.79 NAMPT (0.58) NAMPT
SCHEMBL31489006 0.78 NAMPT (0.61) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed