SCHEMBL31489694

SCHEMBL31489694

CC(=O)C(c1ccc(F)cc1)n1cc(I)c(C)n1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
PTGDR2 Q9Y5Y4 3/20 0.33
CYP1A2 P05177 2/20 0.33
EHMT2 Q96KQ7 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
POLB P06746 1/20 0.32
PTGS2 P35354 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489270 0.78 CYP17A1 (0.38) ALDH1A1CYP1A2KDM4EGAACYP2C9
SCHEMBL31489728 0.78 CYP17A1 (0.38) ALDH1A1CYP1A2KDM4EGAACYP2C9
SCHEMBL31489647 0.76 POLB (0.37) PTGDR2EHMT2POLBHDAC3HDAC4
SCHEMBL31489260 0.74 HDAC3 (0.34) ALDH1A1PTGDR2KDM4EHPGDMAPT
SCHEMBL31489944 0.73 NPC1 (0.32) NPC1RAB9A
SCHEMBL31489284 0.73 NPC1 (0.32) NPC1RAB9A
SCHEMBL31489285 0.71 SMN1; SMN2 (0.34) ALDH1A1PTGDR2HPGDHTTHTR2A
SCHEMBL16679625 0.66 BRD4 (0.30)
SCHEMBL23130243 0.64 NPC1 (0.42) ALDH1A1CYP1A2KDM4EPOLBPTGS2
SCHEMBL31489358 0.64 CYP17A1 (0.39) ALDH1A1CYP1A2KDM4EGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed