SCHEMBL31489718

SCHEMBL31489718

CC(c1ccc(F)cc1)n1ccc(F)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 4/20 0.45
CYP19A1 P11511 2/20 0.36
ALDH1A1 P00352 2/20 0.34
GAA P10253 2/20 0.34
KDM4E B2RXH2 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KCNK3 O14649 4/20 0.33
MET P08581 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD11B1 P28845 1/20 0.32
CHRM1 P11229 2/20 0.32
SLC6A3 Q01959 2/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
HRH1 P35367 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23234015 0.85 CYP2D6 (0.42) CYP17A1CYP19A1ALDH1A1KDM4ECYP2D6
SCHEMBL29300479 0.76
SCHEMBL31489212 0.76 CYP26A1 (0.34) CYP17A1CYP19A1
SCHEMBL31489260 0.75 HDAC3 (0.34) CYP19A1ALDH1A1KDM4EKCNK3
SCHEMBL28331534 0.73 CYP17A1 (0.47) CYP17A1CYP19A1ALDH1A1GAAKDM4E
SCHEMBL31489358 0.70 CYP17A1 (0.39) CYP17A1CYP19A1ALDH1A1GAAKDM4E
SCHEMBL31489601 0.70 CYP17A1 (0.39) CYP17A1CYP19A1ALDH1A1GAAKDM4E
SCHEMBL31489728 0.69 CYP17A1 (0.38) CYP17A1ALDH1A1GAAKDM4ESMN1; SMN2
SCHEMBL31489270 0.69 CYP17A1 (0.38) CYP17A1ALDH1A1GAAKDM4ESMN1; SMN2
SCHEMBL15651476 0.69 CYP17A1 (0.41) CYP17A1CYP19A1ALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed