Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26326631 | 0.98 | DHODH (0.54) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL3051979 | 0.96 | HTR2A (0.55) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL1348883 | 0.91 | HTR2A (0.58) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL30910924 | 0.82 | HTR2A (0.51) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL3303526 | 0.82 | HTR2A (0.51) | HTR2AHTR2CHTR7CYP2D6HTR6 | |
| SCHEMBL16861567 | 0.82 | HTR2A (0.51) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL16861667 | 0.82 | HTR2A (0.51) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL15994961 | 0.82 | HTR2A (0.51) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL16978485 | 0.82 | DHODH (0.44) | HTR2AHTR2CHTR7DHODHCYP2D6 | |
| SCHEMBL21911551 | 0.81 | HTR2A (0.50) | HTR2AHTR2CHTR7DHODHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |