⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341644 | 1.00 | — | — | |
| SCHEMBL1080050 | 1.00 | — | — | |
| SCHEMBL1345224 | 0.99 | — | — | |
| SCHEMBL12341645 | 0.99 | — | — | |
| SCHEMBL4276946 | 0.99 | — | — | |
| SCHEMBL25012457 | 0.99 | — | — | |
| SCHEMBL3990237 | 0.99 | — | — | |
| SCHEMBL3989934 | 0.99 | — | — | |
| SCHEMBL3990002 | 0.99 | — | — | |
| SCHEMBL131456 | 0.99 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411390-A1 | MODULATION OF BACTERIAL QUORUM SENSING WITH SYNTHETIC LIGANDS | WISCONSIN ALUMNI RES FOUND (US) | 2022-12-29 | — | — | US | disclosed |
| US-10702497-B2 | Use of acyl-homoserine lactone derivatives as anti-thrombotic agents | THE UNIVERSITY OF TOLEDO (US) | 2020-07-07 | — | — | US | disclosed |
| US-20200115356-A1 | Modulation of Bacterial Quorum Sensing With Synthetic Ligands | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2020-04-16 | — | — | US | disclosed |
| US-20190111023-A1 | USE OF ACYL-HOMOSERINE LACTONE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | THE UNIVERSITY OF TOLEDO (US) | 2019-04-18 | — | — | US | disclosed |
| US-10195177-B2 | Use of acyl-homoserine lactone derivatives as anti-thrombotic agents | THE UNIVERSITY OF TOLEDO (US) | 2019-02-05 | — | — | US | disclosed |
| US-9796694-B2 | Modulation of bacterial quorum sensing with synthetic ligands | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-10-24 | — | — | US | disclosed |
| US-20150080349-A1 | MODULATION OF BACTERIAL QUORUM SENSING WITH SYNTHETIC LIGANDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2015-03-19 | — | — | US | disclosed |
| US-8815943-B2 | Modulation of bacterial quorum sensing with synthetic ligands | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-08-26 | — | — | US | disclosed |
| US-8269024-B2 | Compounds and methods for modulating communication and virulence in quorum sensing bacteria | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-8269024-B2 | Compounds and methods for modulating communication and virulence in quorum sensing bacteria | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100305182-A1 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | BLACKWELL HELEN E | 2010-12-02 | — | — | US | disclosed |
| US-20100305182-A1 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | BLACKWELL HELEN E | 2010-12-02 | — | — | US | disclosed |
| US-20100305182-A1 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | BLACKWELL HELEN E | 2010-12-02 | — | — | US | disclosed |
| US-7642285-B2 | Compounds and methods for modulating communication and virulence in quorum sensing bacteria | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642285-B2 | Compounds and methods for modulating communication and virulence in quorum sensing bacteria | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642285-B2 | Compounds and methods for modulating communication and virulence in quorum sensing bacteria | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20080312319-A1 | Modulation of Bacterial Quorum Sensing with Synthetic Ligands | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-18 | — | — | US | disclosed |
| EP-1848703-A2 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20060178430-A1 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-08-10 | — | — | US | disclosed |
| WO-2006084056-A2 | COMPOUNDS AND METHODS FOR MODULATING COMMUNICATION AND VIRULENCE IN QUORUM SENSING BACTERIA | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-08-10 | — | — | WO | disclosed |