⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31491045 | 0.84 | — | — | |
| SCHEMBL31490996 | 0.83 | — | — | |
| SCHEMBL30539023 | 0.80 | — | — | |
| SCHEMBL31412230 | 0.78 | — | — | |
| SCHEMBL30099309 | 0.78 | CYP11B1 (0.30) | — | |
| SCHEMBL31412213 | 0.74 | MAPT (0.34) | — | |
| SCHEMBL29592633 | 0.73 | — | — | |
| SCHEMBL26623643 | 0.73 | — | — | |
| SCHEMBL21379233 | 0.73 | — | — | |
| SCHEMBL30699586 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049274-A2 | TETRACYCLIC DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |