Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 4/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23764672 | 1.00 | LRRK2 (0.57) | LRRK2CA1CA2CES1MAP3K7 | |
| SCHEMBL30082282 | 1.00 | LRRK2 (0.57) | LRRK2CA1CA2CES1MAP3K7 | |
| SCHEMBL469844 | 0.90 | KDR (0.50) | LRRK2CA1CA2CES1MAP3K7 | |
| SCHEMBL31492060 | 0.90 | LRRK2 (0.49) | LRRK2CA1CA2CES1MAP3K7 | |
| SCHEMBL469804 | 0.90 | CES1 (0.50) | LRRK2CA1CA2CES1MAP3K7 | |
| SCHEMBL18955405 | 0.86 | CA1 (0.64) | LRRK2CA1CA2CES1ABL1 | |
| SCHEMBL31492045 | 0.83 | LRRK2 (0.52) | LRRK2CA1CA2MAPTKDR | |
| SCHEMBL18974994 | 0.83 | LRRK2 (0.52) | LRRK2CA1CA2MAPTKDR | |
| SCHEMBL31492034 | 0.81 | MAPT (0.50) | LRRK2CA1CA2MAPTSMN1; SMN2 | |
| SCHEMBL31492055 | 0.81 | LRRK2 (0.52) | LRRK2CA1CA2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | disclosed |