Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 10/20 | 0.63 |
| ▸ | USP2 | O75604 | 7/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20455801 | 0.84 | USP2 (0.49) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20455787 | 0.83 | USP2 (0.48) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL9009194 | 0.80 | CYP2D6 (0.55) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2334345 | 0.79 | CYP2D6 (0.53) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL20469057 | 0.77 | OGA (0.52) | OPRM1 | |
| SCHEMBL30490313 | 0.77 | CYP3A4 (0.81) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL19347110 | 0.77 | CYP2D6 (0.84) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL19341580 | 0.77 | CYP2D6 (1.00) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL10260816 | 0.76 | TSHR (0.51) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL19341569 | 0.76 | CYP2D6 (0.83) | CYP2D6USP2CYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076071-A2 | SYNTHESIS OF RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |
| US-20250115551-A1 | SYNTHESIS OF RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2025-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115551-A1 | SYNTHESIS OF RAS INHIBITORS | KRAS, NRAS, HRAS | CYP2D6 2356/4885USP2 973/4885CYP3A4 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.