Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783538 | 0.87 | CYP17A1 (0.40) | CYP17A1RXFP1SYKKCNQ4KCNQ5 | |
| SCHEMBL31093805 | 0.85 | CYP17A1 (0.42) | CYP17A1RXFP1SYKKCNQ4KCNQ5 | |
| SCHEMBL15223288 | 0.85 | ATR (0.44) | CYP17A1RXFP1SYKKCNQ4KCNQ5 | |
| SCHEMBL23500611 | 0.83 | ATR (0.42) | CYP17A1RXFP1SYKKCNQ4KCNQ5 | |
| SCHEMBL5456915 | 0.79 | SYK (0.46) | CYP17A1SYKRORCATRGSK3B | |
| SCHEMBL22049474 | 0.78 | AAK1 (0.43) | CYP17A1RXFP1SYKGABRA1GABRG2 | |
| SCHEMBL29439040 | 0.78 | AAK1 (0.43) | CYP17A1RXFP1SYKGABRA1GABRG2 | |
| SCHEMBL7412985 | 0.78 | SYK (0.42) | CYP17A1SYKRORCATRGSK3B | |
| SCHEMBL23508845 | 0.77 | IDO1 (0.36) | CYP17A1SYKKCNQ4KCNQ5RORC | |
| SCHEMBL15583603 | 0.77 | AAK1 (0.41) | CYP17A1RXFP1SYKKCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025097025-A1 | PROTEIN KINASE C (PKC) THETA INHIBITOR COMPOUNDS | EVOMMUNE, INC. (US) | 2025-05-08 | — | — | WO | disclosed |