⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27158804 | 1.00 | — | — | |
| SCHEMBL31005851 | 0.86 | ATM (0.33) | — | |
| SCHEMBL27159076 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL27158940 | 0.81 | — | — | |
| SCHEMBL24649284 | 0.78 | — | — | |
| SCHEMBL29125157 | 0.72 | — | — | |
| SCHEMBL29230519 | 0.72 | — | — | |
| SCHEMBL31239968 | 0.72 | — | — | |
| SCHEMBL29977229 | 0.72 | — | — | |
| SCHEMBL24697525 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4640684-A1 | KRAS G12D INHIBITORS AND USES THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2025-10-29 | — | — | EP | disclosed |
| CN-119894891-A | KRAS G12D inhibitor and application thereof | 上海和誉生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |