SCHEMBL31499243

SCHEMBL31499243

Cc1cc(-c2cnc3ncn(Cc4ccc(C5CO5)c(F)c4)c3c2)cn(C)c1=O

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.47
BRD9 Q9H8M2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31499226 0.82 BRD4 (0.49) BRD4BRD9
SCHEMBL31499252 0.80 BRD4 (0.52) BRD4BRD9
SCHEMBL31499250 0.79 BRD4 (0.58) BRD4BRD9
SCHEMBL31499232 0.78 BRD4 (0.64) BRD4
SCHEMBL23073125 0.65 BRD4 (0.52) BRD4
SCHEMBL18152849 0.64 BRD4 (0.51) BRD4
SCHEMBL23073006 0.64 BRD4 (0.50) BRD4
SCHEMBL23073127 0.64 BRD4 (0.50) BRD4
SCHEMBL18152753 0.64 BRD4 (0.54) BRD4
SCHEMBL18538437 0.64 BRD4 (0.48) BRD4BRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504726-A BRD4 inhibitor and preparation method and application thereof 四川大学华西医院 2025-02-25 CN disclosed