Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145390 | 0.94 | DPP4 (0.48) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL2098108 | 0.88 | DPP4 (0.48) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL2099460 | 0.88 | DPP4 (0.48) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL3150575 | 0.87 | DPP4 (0.49) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL2097781 | 0.84 | DPP4 (0.49) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL2097778 | 0.84 | DPP4 (0.49) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL2098878 | 0.83 | DPP4 (0.50) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL2098876 | 0.83 | DPP4 (0.50) | DPP4MAP4K4CYP2D6CHRM1HRH1 | |
| SCHEMBL2098253 | 0.79 | MAPT (0.47) | DPP4MAP4K4JAK3BTKPADI4 | |
| SCHEMBL28478050 | 0.77 | DPP4 (0.53) | DPP4MAP4K4JAK3BTKKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863790-B1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | SANOFI AVENTIS (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-1863790-A1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | Sanofi-Aventis (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099943-A1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2006-09-28 | — | — | WO | disclosed |