Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.34 |
| ▸ | KCNT2 | Q6UVM3 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499791 | 0.92 | WRN (0.54) | WRNTSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL31499842 | 0.92 | WRN (0.52) | WRNTSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL31499697 | 0.91 | WRN (0.60) | WRNTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL31499971 | 0.91 | WRN (0.51) | WRNTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL31499577 | 0.90 | WRN (0.53) | WRNTSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL31499884 | 0.89 | WRN (0.61) | WRNTSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL31499595 | 0.87 | WRN (0.54) | WRNTSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL31500603 | 0.86 | WRN (0.48) | WRNTSHRSMN1; SMN2MAPTKDM4E | |
| SCHEMBL31499709 | 0.86 | WRN (0.71) | WRNTSHRSMN1; SMN2KCNT1KCNT2 | |
| SCHEMBL31499956 | 0.84 | WRN (0.43) | WRNMAPTKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |
| CN-119899186-A | Azabicyclo derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-29 | — | — | CN | disclosed |