Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499696 | 0.93 | WRN (0.56) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499968 | 0.92 | WRN (0.55) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499922 | 0.90 | WRN (0.53) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499923 | 0.89 | WRN (0.52) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31295771 | 0.89 | WRN (0.52) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499954 | 0.88 | WRN (0.52) | WRNACHEPOLBALDH1A1TSHR | |
| SCHEMBL31500556 | 0.87 | WRN (0.57) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31499893 | 0.87 | WRN (0.67) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31394090 | 0.86 | WRN (0.53) | WRNACHEPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL25035189 | 0.86 | WRN (0.74) | WRNACHEPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |