Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.34 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.32 |
| ▸ | FES | P07332 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501615 | 0.94 | MEN1 (0.41) | MEN1CTNNB1TCF7L2GRM2HPGD | |
| SCHEMBL31501614 | 0.94 | MEN1 (0.38) | MEN1CTNNB1TCF7L2KIF18AGPR6 | |
| SCHEMBL31501603 | 0.88 | MEN1 (0.41) | MEN1CTNNB1TCF7L2GPR6AURKA | |
| SCHEMBL25273586 | 0.87 | MEN1 (0.46) | MEN1KIF18AAURKA | |
| SCHEMBL30456045 | 0.82 | MEN1 (0.46) | MEN1HTTAURKA | |
| SCHEMBL25271281 | 0.82 | MEN1 (0.46) | MEN1HTTAURKA | |
| SCHEMBL25273634 | 0.81 | MEN1 (0.49) | MEN1CYP2D6AURKA | |
| SCHEMBL31501616 | 0.81 | MEN1 (0.39) | MEN1KIF18A | |
| SCHEMBL31501607 | 0.81 | CTNNB1 (0.42) | MEN1CTNNB1TCF7L2CYP3A4CYP2D6 | |
| SCHEMBL31501704 | 0.79 | HRH4 (0.43) | MEN1CYP3A4CYP2D6CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | claimed |
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | MLLT1, MEN1, BMI1 | MEN1 2/4885CTNNB1 1174/4885TCF7L2 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.