Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31503626 | 1.00 | BTK (0.37) | BTKACEPOLBHTTLMNA | |
| SCHEMBL31503367 | 0.83 | SMN1; SMN2 (0.37) | POLBHTTSMN1; SMN2HSD17B10HPGD | |
| SCHEMBL1908638 | 0.78 | POLB (0.42) | POLBHTTSMN1; SMN2HSD17B10HPGD | |
| SCHEMBL12487514 | 0.76 | HTT (0.40) | POLBHTTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL12487515 | 0.76 | HTT (0.40) | POLBHTTLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL25547180 | 0.74 | BTK (0.50) | BTKACELMNAALDH1A1AKR1C3 | |
| SCHEMBL16886300 | 0.72 | ACE (0.44) | BTKACEPOLBLMNAAKR1C3 | |
| SCHEMBL31503423 | 0.72 | SMN1; SMN2 (0.39) | BTKACELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL31503502 | 0.72 | SMN1; SMN2 (0.39) | BTKACELMNASMN1; SMN2HSD17B10 | |
| SCHEMBL517229 | 0.72 | POLB (0.35) | POLBHTTSMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062334-A1 | 4-((5-(3-(4-(PYRIDIN-2-YL)CYCLOPENTYL)-1 H-PYRAZOL-3-YL)AMINO)-BENZENESULFONAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS CDK INHIBITORS FOR THE TREATMENT OF CANCER | BEIGENE SWITZERLAND GMBH (CH) | 2025-03-27 | — | — | WO | disclosed |