Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 11/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 9/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 9/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31505624 | 0.89 | IKBKB (0.37) | PBRM1SMARCA2SMARCA4ROCK2NR1I2 | |
| SCHEMBL24461178 | 0.83 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL29619442 | 0.83 | PBRM1 (0.41) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL24461447 | 0.82 | PBRM1 (0.43) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL31505643 | 0.80 | JAK3 (0.35) | PBRM1SMARCA2SMARCA4 | |
| SCHEMBL31505601 | 0.80 | JAK3 (0.35) | PBRM1SMARCA2SMARCA4 | |
| SCHEMBL24461321 | 0.76 | IKBKB (0.43) | PBRM1SMARCA2SMARCA4IKBKBCHUK | |
| SCHEMBL24461128 | 0.76 | IKBKB (0.47) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL27053155 | 0.76 | PBRM1 (0.43) | PBRM1SMARCA2SMARCA4NR1I2BRD4 | |
| SCHEMBL27052479 | 0.74 | PBRM1 (0.38) | PBRM1SMARCA2SMARCA4NR1I2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101944-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A | Plexium, Inc. (US) | 2025-05-15 | — | — | WO | disclosed |