SCHEMBL31508375

SCHEMBL31508375

CC12CCC3c4c(cccc4OCCCN)CCC3C1CCC2O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.53
ESR1 P03372 5/20 0.53
LMNA P02545 4/20 0.53
ESR2 Q92731 3/20 0.53
TSHR P16473 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
ALDH1A1 P00352 2/20 0.53
STS P08842 2/20 0.53
MAPT P10636 2/20 0.53
PGR P06401 2/20 0.53
AR P10275 2/20 0.53
SLC6A3 Q01959 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
CYP1A2 P05177 1/20 0.53
HIF1A Q16665 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
SLC22A1 O15245 1/20 0.53
AKR1B10 O60218 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8998250 0.86 HSD17B10 (0.62) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL31508268 0.80 HSD17B10 (0.74) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL31508553 0.80 HSD17B10 (0.74) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL31508415 0.80 HSD17B10 (0.74) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL31508323 0.80 HSD17B10 (0.74) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL31508468 0.80 HSD17B10 (0.74) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL3825574 0.80 HSD17B10 (0.74) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL10811302 0.79 ESR1 (0.60) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL11872663 0.76 HSD17B10 (0.56) HSD17B10ESR1LMNAESR2TSHR
SCHEMBL10715584 0.75 HSD17B10 (0.46) HSD17B10ESR1LMNAESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025097061-A1 ApoB DEGRADING COMPOUNDS AND USES THEREOF AVILAR THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed