Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 20/20 | 0.64 |
| ▸ | KAT7 | O95251 | 19/20 | 0.64 |
| ▸ | KAT6B | Q8WYB5 | 14/20 | 0.64 |
| ▸ | KAT5 | Q92993 | 8/20 | 0.64 |
| ▸ | KAT8 | Q9H7Z6 | 8/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26074265 | 0.91 | KAT6A (0.63) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL30545817 | 0.91 | KAT6A (0.63) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL21609082 | 0.82 | KAT6A (0.58) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL31510990 | 0.82 | KAT6A (0.51) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL21609246 | 0.82 | KAT6A (0.64) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL32681107 | 0.81 | KAT6A (0.53) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL21609172 | 0.80 | KAT6A (0.52) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL21660539 | 0.79 | KAT7 (0.70) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL21609055 | 0.79 | KAT6A (0.66) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL21609035 | 0.79 | KAT6A (0.60) | KAT6AKAT7KAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276966-A1 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives | PFIZER (US) | 2025-09-04 | — | — | US | disclosed |
| US-20250122183-A1 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives | PFIZER (US) | 2025-04-17 | — | — | US | disclosed |
| WO-2025074249-A1 | NITROGEN-LINKED BENZISOXAZOLE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF CANCER | PFIZER INC. (US) | 2025-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122183-A1 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives | CCNI, MKI67, CCNA1 | KAT6A 1852/4885KAT7 2086/4885KAT6B 1517/4885 |
| US-20250276966-A1 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives | CCNI, MKI67, CCNA1 | KAT6A 1862/4885KAT7 2251/4885KAT6B 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.