SCHEMBL31513554

SCHEMBL31513554

Nc1cnc2scnc2c1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 1/20 0.36
PI4K2B Q8TCG2 1/20 0.36
PI4K2A Q9BTU6 1/20 0.36
PI4KB Q9UBF8 1/20 0.36
PIK3CD O00329 1/20 0.34
DYRK1A Q13627 1/20 0.33
DAO P14920 1/20 0.32
MAPKAPK2 P49137 1/20 0.32
RPS6KA3 P51812 1/20 0.32
CSNK2A1 P68400 1/20 0.32
PLK3 Q9H4B4 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EGFR P00533 1/20 0.31
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1053825 1.00 PI4KA (0.36) PI4KAPI4K2BPI4K2API4KBPIK3CD
SCHEMBL31609671 0.74 PIK3CD (0.40) PIK3CDALDH1A1HSD17B10
SCHEMBL1890058 0.74 PIK3CD (0.34) PIK3CDALDH1A1HSD17B10
SCHEMBL15577565 0.74 DYRK1A (0.39) PIK3CDDYRK1AALDH1A1HSD17B10
SCHEMBL969038 0.74 PIK3CD (0.40) PIK3CDALDH1A1HSD17B10
SCHEMBL2054540 0.74 CYP1A2 (0.36) PIK3CDALDH1A1HSD17B10
SCHEMBL18180231 0.69 EGFR (0.36) PIK3CDALDH1A1EGFR
SCHEMBL4281170 0.69 HSD17B10 (0.35) PIK3CDALDH1A1HSD17B10
SCHEMBL20759935 0.69 PIK3CD (0.32) PIK3CD
SCHEMBL22758276 0.69 PIK3CD (0.32) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119855821-A Thiazolo [5,4-b ] pyridine MALT-1 inhibitors 艾伯维公司 2025-04-18 CN disclosed