SCHEMBL31514341

C[C@@H](O)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	7/20	0.38

▸	BACE2	Q9Y5Z0	2/20	0.38

▸	GLP1R	P43220	3/20	0.37

▸	SCTR	P47872	1/20	0.37

▸	CTSD	P07339	1/20	0.37

▸	SLC15A2	Q16348	1/20	0.37

▸	CALCR	P30988	2/20	0.36

▸	CRHR1	P34998	1/20	0.36

▸	CRHR2	Q13324	1/20	0.36

▸	GCGR	P47871	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30600995	0.93	SLC15A2 (0.39)	BACE1BACE2CTSDSLC15A2
SCHEMBL4216003	0.93	CALCR (0.39)	BACE1BACE2CTSDCALCR
SCHEMBL31320779	0.92	CALCR (0.40)	GLP1RSCTRCALCRCRHR1CRHR2
SCHEMBL29530561	0.92	SLC15A2 (0.39)	GLP1RSCTRSLC15A2CALCRCRHR1
SCHEMBL29682077	0.90	CALCR (0.40)	GLP1RSLC15A2CALCR
SCHEMBL29381521	0.90	BACE1 (0.40)	BACE1BACE2GLP1RSCTRCTSD
SCHEMBL29622914	0.89	SLC15A2 (0.38)	SLC15A2CRHR1CRHR2
SCHEMBL29492577	0.89	BACE1 (0.41)	BACE1BACE2GLP1RSCTRCALCR
SCHEMBL4200040	0.89	CALCR (0.39)	GLP1RSLC15A2CALCRCRHR1CRHR2
SCHEMBL4200033	0.89	CALCR (0.39)	GLP1RSLC15A2CALCRCRHR1CRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119776332-A	Enzymatic preparation process of histamine dihydrochloride	上海瀚鸿科技股份有限公司	2025-04-08	—	—	CN	disclosed