Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 6/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.36 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514813 | 0.92 | HDAC1 (0.45) | HDAC1GRM2GPR119PARP1PARP2 | |
| SCHEMBL31514777 | 0.92 | HDAC1 (0.45) | HDAC1GRM2GPR119PARP1PARP2 | |
| SCHEMBL31514767 | 0.89 | GRM2 (0.45) | HDAC1GRM2GPR119IDH1PARP1 | |
| SCHEMBL30979296 | 0.84 | PARP1 (0.47) | HDAC1GRM2GPR119PARP1HSD11B1 | |
| SCHEMBL31474243 | 0.84 | PARP1 (0.47) | HDAC1GRM2GPR119PARP1HSD11B1 | |
| SCHEMBL31097505 | 0.81 | PARP1 (0.38) | PARP1PARP2PARP6PARP3BACE1 | |
| SCHEMBL31514674 | 0.80 | PARP1 (0.46) | HDAC1GRM2GPR119PARP1HSD11B1 | |
| SCHEMBL31514688 | 0.80 | PARP1 (0.46) | HDAC1GRM2GPR119PARP1HSD11B1 | |
| SCHEMBL30869214 | 0.79 | SMARCA2 (0.47) | GPR119PARP1BACE1 | |
| SCHEMBL22912768 | 0.76 | BACE1 (0.53) | PARP1PARP2PARP6PARP3BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025091346-A1 | PARP INHIBITORS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-05-08 | — | — | WO | disclosed |
| WO-2025092905-A1 | PARP INHIBITORS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2025-05-08 | — | — | WO | disclosed |