SCHEMBL31519110

SCHEMBL31519110

CCc1nc(-c2ccc(N)cc2)n(-c2cccc(C(=O)NCCCCn3nccn3)c2)n1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.83
CYP3A4 P08684 3/20 0.83
MYOF Q9NZM1 2/20 0.83
CYP2C19 P33261 1/20 0.83
CYP2D6 P10635 3/20 0.55
CYP1A2 P05177 2/20 0.51
CYP2B6 P20813 2/20 0.51
RXFP1 Q9HBX9 1/20 0.41
SRC P12931 1/20 0.40
CDK8 P49336 4/20 0.38
MAPK14 Q16539 4/20 0.38
PKN2 Q16513 2/20 0.38
CNR1 P21554 1/20 0.38
KDR P35968 1/20 0.38
MAPT P10636 3/20 0.38
TP53 P04637 2/20 0.38
RET P07949 1/20 0.38
PDGFRA P16234 1/20 0.38
GRK5 P34947 1/20 0.38
PRKX P51817 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31519114 1.00 CYP2C9 (0.83) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519108 0.93 CYP2C9 (0.85) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519097 0.92 CYP2C9 (0.84) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519112 0.92 CYP2C9 (0.84) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519087 0.91 CYP2C9 (0.83) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519094 0.91 CYP2C9 (0.83) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519089 0.91 CYP2C9 (0.83) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519075 0.91 CYP2C9 (1.00) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519121 0.90 CYP2C9 (0.98) CYP2C9CYP3A4MYOFCYP2C19CYP2D6
SCHEMBL31519084 0.90 CYP2C9 (0.80) CYP2C9CYP3A4MYOFCYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528884-A 1, 5-Diaryl-1, 2, 4-triazole derivative targeted at Myoferlin as well as synthesis and application thereof 华东师范大学 2025-02-28 CN disclosed