Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | LAP3 | P28838 | 3/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL22285873 | 1.00 | TDP1 (0.67) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL6852797 | 1.00 | TDP1 (0.67) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL7862899 | 0.97 | TDP1 (0.62) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL27549086 | 0.97 | TDP1 (0.62) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL29186483 | 0.97 | TDP1 (0.62) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL29249405 | 0.97 | TDP1 (0.62) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL28091290 | 0.97 | TDP1 (0.62) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL4710370 | 0.94 | TDP1 (0.59) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL28569058 | 0.90 | TDP1 (0.62) | TDP1TSHRALDH1A1ANPEPLAP3 | |
| Propylene Glycol SCHEMBL5486872 | 0.90 | TDP1 (0.62) | TDP1TSHRALDH1A1ANPEPLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114983863-A | Modified alginate composition for skin repair and application thereof | 青岛海之林生物科技开发有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-109232991-B | Hydrophobic SiO2Coated halogen-free intumescent flame retardant and preparation method and application thereof | 武汉轻工大学 | 2020-09-29 | — | — | CN | claimed |
| CN-107474166-B | A kind of polystyrene silver gray thermal insulation material preparation method of mica titanium filling in situ | 武汉轻工大学 | 2019-10-18 | — | — | CN | claimed |
| CN-109232991-A | A kind of hydrophobicity SiO2Halogen-free expanded flame-retardant agent of cladding and its preparation method and application | 武汉轻工大学 | 2019-01-18 | — | — | CN | claimed |
| CN-108219233-A | A kind of gradient fire retardant and preparation method thereof | 襄阳华虹高科新材料有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-107474166-A | Preparation method, its product and the application of a kind of polystyrene silver gray insulation material of graphite titanium filling in situ | 武汉轻工大学 | 2017-12-15 | — | — | CN | claimed |
| CN-105131157-B | Preparation method of mica titanium in-situ filled polystyrene silver gray heat insulation material, product and application thereof | 武汉轻工大学 | 2017-08-04 | — | — | CN | claimed |
| CN-105237661-B | The inhibition that disappears and the synthetic method of synchronous fire-retardant graphite polystyrene material | 武汉轻工大学 | 2017-06-09 | — | — | CN | claimed |
| EP-2225373-A2 | MICROBIAL CONVERSION OF OILS AND FATTY ACIDS TO HIGH-VALUE CHEMICALS | Glycos Biotechnologies, Incorporated (US) | 2010-09-08 | — | — | EP | claimed |
| WO-2009078973-A2 | MICROBIAL CONVERSION OF OILS AND FATTY ACIDS TO HIGH-VALUE CHEMICALS | GLYCOS BIOTECHNOLOGIES, INCORPORATED (US) | 2009-06-25 | — | — | WO | claimed |
| CN-114438172-B | Compositions and methods for single molecule placement on a substrate | 亿明达股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| WO-2024124089-A1 | PERSONAL CARE COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2024-06-13 | — | — | WO | disclosed |
| CN-114391031-B | Aqueous dispersion of polymeric particles | 陶氏环球技术有限责任公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114072477-B | Acrylic adhesive composition | 罗门哈斯公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117715991-A | Electrodepositable coating composition | PPG工业俄亥俄公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-0663918-A1 | PURE ENANTIOMERS OF PHOSPHORIC-ACID ESTERS AS PHOSPHOLIPASE-A2 INHIBITORS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994009014-A1 | PURE ENANTIOMERS OF PHOSPHORIC-ACID ESTERS AS PHOSPHOLIPASE-A2 INHIBITORS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1994-04-28 | — | — | WO | disclosed |
| US-5160725-A | Contrast agent for diagnostic imaging, polyethylene glycol phosphates and carboxylates as stabilizers | SILICA GEL GESELLSCHAFT MBH ADSORPTIONS-TECHNIK, APPARATEBAU (DE) | 1992-11-03 | — | — | US | disclosed |
| US-4561962-A | CROSSLINKED ALLYL COPOLYMER CONTAINING ION TO BE DETERMINED | FLUILOGIC SYSTEMS OY (FI) | 1985-12-31 | — | — | US | disclosed |
| US-4166005-A | CULTIVATING A MEMBER OF THE LACTOBACILLACEAE FAMILY, PROMOTER | EASTMAN KODAK COMPANY (US) | 1979-08-28 | — | — | US | disclosed |