Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.46 |
| ▸ | CD38 | P28907 | 7/20 | 0.43 |
| ▸ | NCF1 | P14598 | 4/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20950907 | 0.82 | TEK (0.43) | CD38DYRK1ACHEK1CHEK2 | |
| SCHEMBL26260195 | 0.79 | DYRK1A (0.49) | CD38DYRK1APRMT5WDR77 | |
| SCHEMBL26260216 | 0.77 | DYRK1A (0.47) | CD38DYRK1APRMT5WDR77 | |
| SCHEMBL4020749 | 0.74 | PIK3CD (0.50) | CD38NOS2DYRK1ACHEK1CHEK2 | |
| SCHEMBL7457053 | 0.73 | CYP11B1 (0.50) | CD38DYRK1A | |
| SCHEMBL16159853 | 0.72 | DYRK1A (0.46) | CD38DYRK1ACHEK1CHEK2 | |
| SCHEMBL29441698 | 0.71 | MAP4K4 (0.53) | CD38DYRK1ACHEK1CHEK2 | |
| SCHEMBL14320363 | 0.71 | MAP4K4 (0.53) | CD38DYRK1ACHEK1CHEK2 | |
| SCHEMBL16159089 | 0.71 | DYRK1A (0.50) | CD38DYRK1A | |
| SCHEMBL14320606 | 0.71 | APP (0.50) | CD38DYRK1ACHEK1CHEK2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661432-A | PRMT5 inhibitor, and pharmaceutical composition, pharmaceutical preparation and application thereof | 北京福元医药股份有限公司 | 2025-03-21 | — | — | CN | disclosed |