Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 10/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 12/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458458 | 1.00 | FGFR4 (0.46) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL24458503 | 0.93 | RET (0.45) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL31523837 | 0.93 | RET (0.45) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL24458531 | 0.93 | RET (0.45) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL24458867 | 0.92 | ITK (0.51) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL24458976 | 0.90 | FGFR2 (0.50) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL24458372 | 0.90 | ITK (0.44) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL24458459 | 0.89 | ITK (0.47) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL31523951 | 0.89 | ITK (0.47) | FGFR4FGFR1FGFR2ITKFGFR3 | |
| SCHEMBL24458633 | 0.88 | ITK (0.46) | FGFR4FGFR1FGFR2ITKFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154154-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. | 2025-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154154-A1 | SRC INHIBITORS AND USES THEREOF | SRC, LCK, FYN | FGFR4 425/4885FGFR1 224/4885FGFR2 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.