Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | BRAF | P15056 | 4/20 | 0.50 |
| ▸ | RAF1 | P04049 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | WNT1 | P04628 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31524109 | 0.81 | MAPT (0.58) | MAPK14RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL31524185 | 0.80 | GAA (0.62) | BRAFL3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19070454 | 0.79 | MAPT (0.59) | RAB9ANPC1SMN1; SMN2LMNAKCNQ3 | |
| SCHEMBL13585159 | 0.79 | MAPK14 (0.71) | MAPK14BRAFRAF1MAPK11 | |
| SCHEMBL4700667 | 0.79 | NPC1 (0.56) | BRAFRAF1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29878393 | 0.79 | NPC1 (0.56) | BRAFRAF1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14350415 | 0.78 | MAPK14 (0.69) | MAPK14BRAFRAF1 | |
| SCHEMBL5897054 | 0.77 | MAPK14 (0.65) | MAPK14BRAFRAF1RAB9ASMN1; SMN2 | |
| SCHEMBL29877984 | 0.75 | RAF1 (0.58) | BRAFRAF1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11346493 | 0.75 | KDM4E (0.50) | MAPK14AURKARPS6KB1AURKBWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250152593-A1 | p38 MAPK INHIBITORS AND USES THEREOF | HOPE CITY (US) | 2025-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250152593-A1 | p38 MAPK INHIBITORS AND USES THEREOF | MAPK8, MAPK1, MAPK7 | MAPK14 28/4885BRAF 49/4885RAF1 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.