SCHEMBL31524176

SCHEMBL31524176

Clc1cc(C2CCC2)[13c](Cl)nn1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
CEL P19835 2/20 0.32
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2647857 1.00 TDP1 (0.40) TDP1CELPSMB5
SCHEMBL30833923 1.00 TDP1 (0.40) TDP1CELPSMB5
SCHEMBL29986193 0.96 TDP1 (0.40) TDP1CELPSMB5
SCHEMBL1202161 0.96 TDP1 (0.40) TDP1CELPSMB5
SCHEMBL8111724 0.94 TDP1 (0.36) TDP1CEL
SCHEMBL29987339 0.94 TDP1 (0.39) TDP1CELPSMB5
SCHEMBL10845597 0.94 TDP1 (0.39) TDP1CELPSMB5
SCHEMBL1188150 0.91 TDP1 (0.43) TDP1
SCHEMBL29919389 0.91 TDP1 (0.43) TDP1
SCHEMBL2662122 0.90 TDP1 (0.36) TDP1CEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454069-B 1,2, 4-Triazine-3, 5-dione compound, and preparation method and application thereof 昆药集团股份有限公司 2025-03-14 CN disclosed