Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | CTSS | P25774 | 6/20 | 0.37 |
| ▸ | CTSK | P43235 | 6/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842461 | 0.80 | ATM (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL30133471 | 0.80 | ATM (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL5548155 | 0.80 | ATM (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL20830130 | 0.78 | PPARA (0.37) | IDO1PPARAPPARGCTSSCTSK | |
| SCHEMBL20974785 | 0.78 | PPARA (0.57) | IDO1PPARAPPARGCTSSCTSK | |
| SCHEMBL17291652 | 0.78 | PPARA (0.57) | IDO1PPARAPPARGCTSSCTSK | |
| SCHEMBL15448116 | 0.78 | PPARA (0.57) | IDO1PPARAPPARGCTSSCTSK | |
| SCHEMBL10080538 | 0.77 | ATM (0.46) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL5220048 | 0.76 | ATM (0.45) | PPARAPPARGCTSSCTSKCTSL | |
| SCHEMBL31232348 | 0.76 | ATM (0.45) | PPARAPPARGCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076235-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-04-10 | — | — | WO | disclosed |