Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 7/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.54 |
| ▸ | KRAS | P01116 | 13/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31527324 | 0.92 | MAPK3 (0.54) | MAPK3MAPK1KRAS | |
| SCHEMBL31527098 | 0.92 | MAPK3 (0.54) | MAPK3MAPK1KRAS | |
| SCHEMBL31527333 | 0.92 | MAPK3 (0.54) | MAPK3MAPK1KRAS | |
| SCHEMBL31527524 | 0.92 | MAPK3 (0.53) | MAPK3MAPK1KRAS | |
| SCHEMBL31527583 | 0.92 | MAPK3 (0.65) | MAPK3MAPK1KRAS | |
| SCHEMBL31527060 | 0.91 | MAPK3 (0.56) | MAPK3MAPK1KRAS | |
| SCHEMBL29322103 | 0.89 | MAPK3 (0.48) | MAPK3MAPK1KRAS | |
| SCHEMBL29322134 | 0.88 | KRAS (0.50) | MAPK3MAPK1KRAS | |
| SCHEMBL29321811 | 0.87 | MAPK3 (0.54) | MAPK3MAPK1KRAS | |
| SCHEMBL29321789 | 0.86 | MAPK3 (0.47) | MAPK3MAPK1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076523-A1 | RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |