Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 8/20 | 0.60 |
| ▸ | CDC7 | O00311 | 3/20 | 0.50 |
| ▸ | BUB1 | O43683 | 6/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529936 | 1.00 | MAPKAPK2 (0.60) | MAPKAPK2CDC7BUB1EGFR | |
| SCHEMBL31529860 | 0.79 | CDC7 (0.44) | MAPKAPK2CDC7 | |
| SCHEMBL31529797 | 0.79 | MAPKAPK2 (0.66) | MAPKAPK2 | |
| SCHEMBL3579503 | 0.79 | MAPKAPK2 (0.66) | MAPKAPK2CDC7 | |
| SCHEMBL1909391 | 0.75 | MAPKAPK2 (0.62) | MAPKAPK2 | |
| SCHEMBL792914 | 0.73 | PARP10 (0.58) | MAPKAPK2CDC7 | |
| SCHEMBL426351 | 0.73 | CDC7 (0.41) | MAPKAPK2CDC7BUB1 | |
| SCHEMBL31529806 | 0.72 | MAPKAPK2 (0.58) | MAPKAPK2 | |
| SCHEMBL30625731 | 0.72 | BUB1 (0.64) | MAPKAPK2CDC7BUB1EGFR | |
| SCHEMBL30935099 | 0.71 | MAPKAPK2 (0.57) | MAPKAPK2CDC7BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096869-A1 | PYRROLO-ISOQUINOLINE COMPOUNDS AND THEIR USE IN THERAPY | MATCHPOINT THERAPEUTICS INC. (US) | 2025-05-08 | — | — | WO | disclosed |