Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.63 |
| ▸ | KIT | P10721 | 14/20 | 0.63 |
| ▸ | FLT3 | P36888 | 10/20 | 0.63 |
| ▸ | MET | P08581 | 5/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.54 |
| ▸ | LTK | P29376 | 1/20 | 0.54 |
| ▸ | GRK5 | P34947 | 1/20 | 0.54 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.54 |
| ▸ | FRK | P42685 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423711 | 0.78 | KDR (1.00) | KDRKITFLT3METSRC | |
| SCHEMBL420317 | 0.77 | KIT (1.00) | KDRKITFLT3SRCABL1 | |
| SCHEMBL424318 | 0.76 | KIT (1.00) | KDRKITFLT3METSRC | |
| SCHEMBL5301508 | 0.76 | KDR (0.62) | KDRKITFLT3METSRC | |
| SCHEMBL31531246 | 0.74 | KIT (0.65) | KDRKITFLT3MET | |
| SCHEMBL420858 | 0.74 | KDR (0.63) | KDRKITFLT3METSRC | |
| SCHEMBL31531400 | 0.73 | KDR (0.68) | KDRKITFLT3METSRC | |
| SCHEMBL422109 | 0.73 | KIT (1.00) | KDRKITFLT3METSRC | |
| SCHEMBL420576 | 0.73 | KIT (1.00) | KDRKITFLT3METSRC | |
| SCHEMBL28757593 | 0.72 | KDR (0.53) | KDRKITFLT3METSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638639-A | Biaryl compound with anti-cell necrotic apoptosis activity, derivative and application thereof | 中国药科大学 | 2025-03-18 | — | — | CN | disclosed |