Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21772236 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1MAPTMEN1POLB | |
| SCHEMBL20434223 | 0.83 | KDM4E (0.63) | KDM4EALDH1A1MAPTMEN1POLB | |
| SCHEMBL23142108 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1MAPTIL1RNERAP2 | |
| SCHEMBL9404932 | 0.78 | CSNK2A2 (0.52) | KDM4EALDH1A1MAPTMEN1POLB | |
| SCHEMBL2294753 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL18048363 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1IL1RNERAP2ERAP1 | |
| SCHEMBL31140091 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1IL1RNERAP2ERAP1 | |
| SCHEMBL23832881 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1IL1RNERAP2ERAP1 | |
| SCHEMBL12261417 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1IL1RNERAP2ERAP1 | |
| SCHEMBL30933933 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1IL1RNERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638639-A | Biaryl compound with anti-cell necrotic apoptosis activity, derivative and application thereof | 中国药科大学 | 2025-03-18 | — | — | CN | disclosed |