SCHEMBL31531344

SCHEMBL31531344

COC(=O)c1scc(C)c1NC(=O)C[N+](C)(C)CC(=O)Nc1cc2ccccc2cn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
POLB P06746 1/20 0.53
CYP2C19 P33261 1/20 0.53
NOTUM Q6P988 1/20 0.49
MTOR P42345 1/20 0.42
KDM4E B2RXH2 2/20 0.42
HTT P42858 2/20 0.42
WNT3A P56704 3/20 0.41
MAPT P10636 2/20 0.40
PKM P14618 1/20 0.40
ATM Q13315 1/20 0.40
HTR1A P08908 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
ALDH1A1 P00352 2/20 0.39
USP2 O75604 1/20 0.37
GSK3B P49841 1/20 0.37
DYRK1A Q13627 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31531369 0.82 CYP1A2 (0.62) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531368 0.77 CYP1A2 (0.67) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531340 0.77 CYP1A2 (0.51) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531341 0.76 CYP1A2 (0.56) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531251 0.76 CYP1A2 (0.56) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531252 0.73 CYP1A2 (0.49) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531321 0.72 CYP1A2 (0.51) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531309 0.71 CYP1A2 (0.50) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL31531328 0.69 CYP1A2 (0.47) CYP1A2CYP3A4POLBCYP2C19KDM4E
SCHEMBL5061065 0.69 POLB (0.64) CYP1A2CYP3A4POLBCYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025093590-A1 HETEROARYL ESTER DERIVATIVES AS SODIUM CHANNEL INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-05-08 WO claimed