Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.59 |
| ▸ | KIT | P10721 | 13/20 | 0.59 |
| ▸ | FLT3 | P36888 | 10/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.58 |
| ▸ | PIM1 | P11309 | 2/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.58 |
| ▸ | PRKACA | P17612 | 2/20 | 0.58 |
| ▸ | LTK | P29376 | 2/20 | 0.58 |
| ▸ | GRK5 | P34947 | 2/20 | 0.58 |
| ▸ | CDK8 | P49336 | 2/20 | 0.58 |
| ▸ | CDK7 | P50613 | 2/20 | 0.58 |
| ▸ | CDK9 | P50750 | 2/20 | 0.58 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.58 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.58 |
| ▸ | MST1R | Q04912 | 2/20 | 0.58 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419502 | 0.76 | KDR (0.62) | KDRKITFLT3MAP4K4PDGFRB | |
| SCHEMBL29968270 | 0.76 | KDR (0.62) | KDRKITFLT3MAP4K4PDGFRB | |
| SCHEMBL24288738 | 0.75 | KDR (0.64) | KDRKITFLT3MAP4K4PDGFRB | |
| SCHEMBL423711 | 0.75 | KDR (1.00) | KDRKITFLT3MAP4K4PDGFRB | |
| SCHEMBL31531281 | 0.74 | KDR (0.64) | KDRKITFLT3MAP4K4PDGFRB | |
| SCHEMBL31531418 | 0.74 | KDR (0.64) | KDRKITFLT3MAP4K4PDGFRB | |
| SCHEMBL398355 | 0.72 | NPC1 (0.61) | LRRK2NPC1 | |
| SCHEMBL5441099 | 0.72 | PI4K2A (0.49) | DYRK1ALRRK2DYRK1BLCKNPC1 | |
| SCHEMBL31531347 | 0.71 | KDR (0.63) | KDRKITFLT3MAP4K4PDGFRB | |
| SCHEMBL31531400 | 0.71 | KDR (0.68) | KDRKITFLT3MAP4K4PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638639-A | Biaryl compound with anti-cell necrotic apoptosis activity, derivative and application thereof | 中国药科大学 | 2025-03-18 | — | — | CN | disclosed |