SCHEMBL31536364

SCHEMBL31536364

CCOC(=O)c1cc2cc3ccccc3sc-2cc1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.51
HPGD P15428 6/20 0.51
MAPT P10636 4/20 0.51
RAB9A P51151 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
HSD17B10 Q99714 3/20 0.51
GAA P10253 3/20 0.51
ALOX15 P16050 2/20 0.51
JAK2 O60674 1/20 0.51
JAK3 P52333 1/20 0.51
FOS P01100 1/20 0.47
JUN P05412 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
CNR2 P34972 1/20 0.47
LMNA P02545 2/20 0.46
TSHR P16473 1/20 0.46
KDM4E B2RXH2 4/20 0.45
MEN1 O00255 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15028923 0.80 JAK2 (0.56) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL7681070 0.80 CA12 (0.60) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL13305638 0.79 APP (0.54) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL31536360 0.79 JAK2 (0.50) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL289667 0.77 JAK2 (0.49) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL3393014 0.76 JAK2 (0.53) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL15025443 0.76 JAK2 (0.53) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL29913871 0.75 BCL2L1 (0.57) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL4405770 0.75 BCL2L1 (0.57) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL25744704 0.74 JAK2 (0.51) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114129544-B Ultraviolet curable hydrogel resin for transdermal administration, hydrogel, and cataplasm comprising same Icure药品株式会社 2025-03-21 CN disclosed