Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 19/20 | 0.73 |
| ▸ | ROCK1 | Q13464 | 18/20 | 0.73 |
| ▸ | RPS6KA1 | Q15418 | 17/20 | 0.73 |
| ▸ | RPS6KA5 | O75582 | 8/20 | 0.58 |
| ▸ | AKT2 | P31751 | 9/20 | 0.57 |
| ▸ | AKT3 | Q9Y243 | 5/20 | 0.57 |
| ▸ | CIT | O14578 | 1/20 | 0.46 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.46 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ULK1 | O75385 | 1/20 | 0.46 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | SMC2 | O95347 | 1/20 | 0.46 |
| ▸ | LATS1 | O95835 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31540347 | 0.88 | AKT1 (0.73) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| SCHEMBL31540348 | 0.83 | AKT1 (0.72) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| SCHEMBL5066280 | 0.73 | AKT1 (0.80) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| Trifluoroacetic Acid SCHEMBL3488625 | 0.70 | AKT1 (0.88) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| SCHEMBL3488629 | 0.70 | AKT1 (0.76) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| Hydrochloric Acid SCHEMBL4297263 | 0.69 | AKT1 (0.79) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| Trifluoroacetic Acid SCHEMBL5063569 | 0.69 | AKT1 (0.81) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| SCHEMBL4066879 | 0.68 | AKT1 (0.84) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| SCHEMBL4296447 | 0.68 | AKT1 (0.75) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 | |
| SCHEMBL4965920 | 0.66 | AKT1 (0.73) | AKT1ROCK1RPS6KA1RPS6KA5AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101867-A1 | CELL-IMPERMEABLE AKT INHIBITORS AND PDPK1 INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2025-05-15 | — | — | WO | disclosed |