Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.55 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
| ▸ | CIT | O14578 | 3/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | PRKACA | P17612 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84365 | 0.85 | PRKCI (0.53) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL8688105 | 0.82 | PRKCI (0.55) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL31541439 | 0.82 | PRKCI (0.50) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL31541393 | 0.82 | PRKCI (0.50) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL23021726 | 0.82 | PRKCI (0.50) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL24492983 | 0.82 | PRKCI (0.50) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL8687438 | 0.82 | CIT (0.59) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL23004035 | 0.79 | PRKCI (0.47) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL1439912 | 0.78 | PRKCI (0.50) | PRKCIAXLCITAURKBROCK1 | |
| SCHEMBL28326907 | 0.78 | PRKCI (0.53) | PRKCIAXLCITAURKBROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061029-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2025-03-27 | — | — | WO | disclosed |