Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 20/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3159645 | 0.85 | P2RY1 (0.81) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3150018 | 0.84 | P2RY1 (0.78) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3154843 | 0.84 | P2RY1 (0.76) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3154195 | 0.83 | P2RY1 (0.72) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3146508 | 0.82 | P2RY1 (0.80) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3158698 | 0.82 | P2RY1 (0.77) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3154572 | 0.81 | P2RY1 (1.00) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3159849 | 0.80 | P2RY1 (0.82) | P2RY1KCNH2P2RY14 | |
| SCHEMBL5175962 | 0.80 | P2RY1 (0.72) | P2RY1KCNH2P2RY14 | |
| SCHEMBL3150816 | 0.80 | P2RY1 (0.74) | P2RY1KCNH2P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751113-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-03-10 | — | — | EP | claimed |