Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.66 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105775 | 0.93 | GSK3B (0.74) | GSK3BNR4A2FFAR1ALDH1A1VNN1 | |
| SCHEMBL5868969 | 0.85 | GSK3B (0.68) | GSK3BFFAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6930593 | 0.84 | MAPT (0.53) | GSK3BLMNASMN1; SMN2KMT2A | |
| SCHEMBL13571053 | 0.83 | GSK3B (0.66) | GSK3BFFAR1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14982182 | 0.81 | GSK3B (0.68) | GSK3BALDH1A1CYP2C19CYP1A2LMNA | |
| SCHEMBL1712250 | 0.81 | GSK3B (0.72) | GSK3BALDH1A1GAAVNN1KMT2A | |
| SCHEMBL6091829 | 0.81 | GSK3B (0.62) | GSK3BFFAR1LMNAVNN1HDAC3 | |
| SCHEMBL19707531 | 0.81 | GSK3B (0.62) | GSK3BGAAGPR139 | |
| SCHEMBL2561581 | 0.80 | GSK3B (0.66) | GSK3BALDH1A1VNN1KMT2AGPR139 | |
| SCHEMBL19707546 | 0.80 | GSK3B (0.60) | GSK3BALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638633-A | Method for preparing pyridazinone compound and application thereof | 深圳市华先医药科技有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119638633-A | Method for preparing pyridazinone compound and application thereof | 深圳市华先医药科技有限公司 | 2025-03-18 | — | — | CN | disclosed |